MOTS-c
From £20
In stock, ships today
- Purity: ≥99% (HPLC)
- Form: Yellow to off-white crystalline powder
- Independent lab report for the batch you receive
- For laboratory research use only
£45
- Only 33 left in the UK warehouse
- Order within 12h 10m for dispatch today, estimated delivery Thu 12 Nov
- Free UK delivery over £100
- Discreet, plain unbranded packaging
Third-party lab report
Batch AMQ50.145 99% purity Tested 16 Mar 2026
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About 5-Amino-1MQ
5-Amino-1MQ (5-amino-1-methylquinolinium iodide) is a low-molecular-weight, membrane-permeable small molecule used in preclinical research as a selective inhibitor of nicotinamide N-methyltransferase (NNMT). As a quinolinium derivative rather than a peptide-based inhibitor, it readily enters cells and is used as a research tool in studies of NNMT-mediated biochemical pathways.
Primary areas of investigation
- NNMT enzymatic inhibition studies
- Nicotinamide salvage pathway research
- SAM/methyl-donor cycle investigation
- Adipocyte signalling models
- Skeletal muscle cell line research
- NAD+ biochemical homeostasis
Mechanism
5-Amino-1MQ acts as a substrate-competitive inhibitor of NNMT, the enzyme that catalyses the methylation of nicotinamide using S-adenosyl-L-methionine (SAM) as a methyl donor. In experimental systems, inhibition of NNMT is investigated for its effects on intracellular nicotinamide availability, SAM utilisation, and downstream methylation reactions in controlled laboratory models.
Delivery and returns
Shipped in plain, unbranded packaging from our United Kingdom warehouse. Damaged on arrival? Tell us within 48 hours and we’ll put it right. Shipping and returns
For laboratory research use only. Not for human or veterinary use.
