UK Tracked 24 Dispatch
Fast, tracked shipping from our UK facility. Place order by 2pm for Same Day Dispatch Mon-Fri.
Temperature-Controlled Storage
All peptides maintained at -20C to -22C prior to shipment.
Bundles
Price Range
£37.00
Analysis Total
£37.00 GBP
Certificate of Analysis (COA)
DOWNLOAD LATEST HPLC VERIFICATION
CJC-1295 (without DAC), also known as Modified GRF 1-29, is a synthetic tetrasubstituted analogue of the endogenous Growth Hormone Releasing Hormone (GHRH). Unlike the full 44-amino acid GHRH, this peptide corresponds to the first 29 amino acids (the bioactive core), with four specific amino acid substitutions designed to enhance resistance to enzymatic cleavage by DPP-IV. This version lacks the Drug Affinity Complex (DAC), resulting in a shorter pharmacokinetic profile mimicking natural pulsatile secretion.
The peptide functions as a selective agonist of the GHRH receptor. Upon binding to the pituitary somatotrophs, it stimulates the pulsatile release of growth hormone. Research focuses on its ability to preserve the physiological pulsatile pattern of GH secretion rather than creating a continuous "bleed" of hormone (as seen with DAC variants). It is frequently studied in combination with GHRPs (like Ipamorelin) to investigate synergistic effects on the somatotropic axis.
This product is sold for in-vitro laboratory research purposes only. It is not a drug, food, or cosmetic and is not intended for human or veterinary consumption. All handling should be performed by qualified professionals in a controlled laboratory setting. Forge Peptides is not liable for any misuse of this product. By purchasing, you agree that you are a qualified researcher or a scientific professional.
